Recombinant Human Interleukin-22

Cat No.

RP01517

Product Specifications

Product Type

Recombinant protein

Applications

Bioactivity, Endotoxin

Source

E. coli.

UniProt No.Q9GZX6
Purity

> 97 % by SDS-PAGE and HPLC analyses.

Bioactivity

Fully biologically active when compared to standard. The ED50 as determined by inducing IL-10 secretion of human COLO 205 cells is less than 0.3 ng/ml, corresponding to a specific activity of > 3.3 × 106 IU/mg.

Endotoxin

Less than 1 EU/μg of rHuIL-22 as determined by LAL method.

Molecular Weight

Approximately 33.6 kDa, non-disulfide-linked homodimeric protein containing of two 147 amino acid polypeptide chains.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 5.0.

Alternative Names

IL-22, IL-21, IL22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, Human

Storage

-20C

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Research Area

Immunology